Emerging therapies & exam strategy
What's changing in each specialty: the trials, agents and guideline shifts most likely to matter for the FRACP Divisional Written Exam.
Emerging Therapies and Interventions in Epilepsy
Epilepsy care keeps advancing on multiple fronts — new antiseizure medications with novel mechanisms, precision neuromodulation, and better imaging for surgical planning. Around a third of people…
Migraine: Emerging Therapies and Innovations
Migraine affects over a billion people and is a leading cause of disability. The past decade's therapeutic revolution — targeting the CGRP pathway — has matured, and the field is now beginning to…
Emerging Therapies for Myasthenia Gravis
Myasthenia gravis (MG) is a chronic autoimmune disease of the neuromuscular junction causing fluctuating, fatigable weakness. Its treatment has been transformed in just a few years: alongside the…
Emerging Therapies for Lambert-Eaton Myasthenic Syndrome
Lambert-Eaton myasthenic syndrome (LEMS) is a rare autoimmune disorder of the neuromuscular junction, marked by proximal weakness, autonomic dysfunction, and reduced reflexes. It is often…
Emerging Therapies and Innovations in Neuro-Ophthalmology
Neuro-ophthalmology is being reshaped on two fronts at once: imaging and diagnostics that detect optic-nerve disease earlier and more precisely, and new pharmacologic and gene-based therapies for…
Emerging Therapies in Muscular Dystrophies (Duchenne, Limb-Girdle, Myotonic)
The muscular dystrophies are genetic muscle-wasting disorders, and Duchenne muscular dystrophy (DMD) in particular has seen a rush of new therapies — gene transfer, exon skipping, and the first…
Emerging Therapies in Acute Ischemic Stroke: Tenecteplase and the Extended Window
For two decades, intravenous thrombolysis for acute ischemic stroke was governed by the clock: treat within 4.5 hours or not at all. That paradigm is now shifting toward a "tissue over time"…
Emerging Therapies for Guillain-Barré Syndrome
Guillain-Barré syndrome (GBS) is an acute, often rapidly progressive immune-mediated neuropathy. For roughly four decades its treatment has rested on two pillars — intravenous immunoglobulin (IVIg)…
Diagnostic and Therapeutic Advances in CNS Infections
Central nervous system infections — meningitis, encephalitis, and brain abscess — remain high-morbidity, high-mortality conditions, made harder by multidrug resistance and by the growing population…
Emerging Therapies for Motor Neuron Disease / ALS
Amyotrophic lateral sclerosis remains rapidly progressive and ultimately fatal, but the last few years have brought real movement — particularly for genetically defined subgroups — along with an…
Emerging Therapies for Parkinson's Disease
Parkinson's disease remains progressive and, so far, incurable — symptomatic treatment is still built around dopamine. The great hope of the past decade has been disease modification: slowing the…
Emerging Therapies for Huntington's Disease
Huntington's disease is a fatal, inherited neurodegeneration caused by a CAG-repeat expansion in the HTT gene. For years, disease-modifying therapy proved elusive — but the field has just recorded…
Emerging Therapies in Tourette Syndrome
Tourette syndrome, a neurodevelopmental disorder of motor and phonic tics, has long relied on behavioral therapy first-line and, when medication is needed, on dopamine D2-blocking antipsychotics with…
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